Tolerance is a phenomenon that can occur with any drug, not just illicit drugs.

Tolerance occurs when the body becomes less responsive to a drug over time.

Tolerance can lead to increased drug use as people try to achieve the same effect.

Tolerance can lead to physical and psychological dependence on a drug.

Tolerance can be short-lived or long-lasting.

Tolerance can be partial or complete.

Tolerance can develop to the therapeutic effects of a drug as well as to the side effects.

Tolerance is a major factor in the development of addiction.

Tolerance can be reversed if drug use is stopped.

Tolerance can vary from person to person.