Tolerance is a phenomenon that can occur with any drug, not just illicit drugs.

Tolerance occurs when the body becomes less responsive to a drug over time.

[{"selector":"#anim-0c283f8e-984e-443f-ab42-c3a4b360af95","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-b8481de4-fe31-425d-a53f-e5534707fbf7","keyframes":{"transform":["translate3d(128.62597%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}]

Tolerance can lead to increased drug use as people try to achieve the same effect.

[{"selector":"#anim-05f51666-d3dd-46e6-871d-de19070e9073","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d79dd135-acc3-4a49-9c12-06762cdd4ccc","keyframes":{"transform":["translate3d(-118.32062%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}]

Tolerance can lead to physical and psychological dependence on a drug.

[{"selector":"#anim-ef8273a7-a57f-4a9a-ada6-014ede26a401","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-60c1814a-124f-43d5-979b-3acdc22db7d2","keyframes":{"transform":["translate3d(114.92064%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}]

Tolerance can be short-lived or long-lasting.

[{"selector":"#anim-53d7dbe3-4939-40f1-bc4f-fa56b3763e78","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-edcf5c6e-57fb-4aec-87c6-1d593373b1b9","keyframes":{"transform":["translate3d(-115.87301%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}]

Tolerance can be partial or complete.

[{"selector":"#anim-005c45dd-8c0a-4e70-bd7c-a21546d09e74","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-d51436b0-9465-469b-a0f6-7bf09e264a35","keyframes":{"transform":["translate3d(116.20690%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}]

Tolerance can develop to the therapeutic effects of a drug as well as to the side effects.

[{"selector":"#anim-012cf15c-0d26-4aee-b256-89b9a24e5988","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-58af2192-a593-4f94-bb14-7afee019c3fb","keyframes":{"transform":["translate3d(-116.55173%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] Awareness

Tolerance is a major factor in the development of addiction.

[{"selector":"#anim-8ab5f679-cd3e-4482-92b0-f3a2e5b44d15","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-512ec6f4-bda7-408d-b52c-8970487d9eb6","keyframes":{"transform":["translate3d(116.20690%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}]

Tolerance can be reversed if drug use is stopped.

[{"selector":"#anim-3a495365-c9c9-4c5b-9ea5-8d3f8ea93e9e","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-e37ff38c-4a5d-4bf9-959b-e477d2611689","keyframes":{"transform":["translate3d(-116.55173%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}]

Tolerance can vary from person to person.

[{"selector":"#anim-1a96ed9e-c0b1-4a17-98ac-9768126c6223","keyframes":{"opacity":[0,1]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}] [{"selector":"#anim-11f08283-41ba-4e52-a9a7-0681eba10000","keyframes":{"transform":["translate3d(121.37930%, 0px, 0)","translate3d(0px, 0px, 0)"]},"delay":0,"duration":600,"easing":"cubic-bezier(0.2, 0.6, 0.0, 1)","fill":"both"}]